The Standard Group of Companies design and manufacture Barrier Isolators and Glove Boxes for the Pharmaceutical and Chemical Industries.

The Schematic part of the business uses client specific requirements and follow cGMP and cGAMP standards for standard and bespoke applications.

Both of these pieces of equipment are used widely in similar applications however are fundamentally different.

Glove boxes

A glove box is a sealed container that allows for the handling of objects where a separate environment is required.

They are commonly used to protect workers from hazardous materials or to protect chemicals and materials that may be sensitive to air or water vapor.

Glove boxes may be used under either positive or negative pressure.

Glove boxes operated under positive pressure usually contain materials which are very susceptible to outside contaminates.

Exposure to outside contaminates can lead to a negative effect on the compound being used.

Negative pressure glove boxes are used to protect workers and are used for hazardous and toxic materials like pathogens.

Gloves are built into the glove box and placed so that that the user can manipulate and perform tasks inside the box without breaking containment.

Glove boxes have transparent parts and allow the user to see what is being handled.

These transparent parts are usually fragile and can break in operation.

Schematic industries glove boxes 1


Barrier Isolators

Again, the operation requires the handling of gloves so users can work in accordance with procedures for that process, however this manipulation and view of work in progress is in a sealed and separate environment.

Unlike simple glove boxes, barrier isolators are usually built with stainless steel, are welded and in certain cases the transparent clear parts are substituted with tempered glass or other materials that provide a greater degree of operator safety.

A barrier isolator provides a physical barrier between personnel and the compounding activity where there is the possibility that altercations in the room airflow or poor aseptic technique by the user will introduce contaminants to the work area.

An isolator provides an additional level of protection as the sterile product is not exposed to the room environment or to compounding operator directly. When using an isolator material is passed into the main working chamber through an enclosed pass-thru chamber and accessed through glove ports to perform aseptic manipulations.


Standard Group sterility test barrier isolator 1


 Key differences between a Glove Box and a Barrier Isolator

Version 3 glove box

For more information click here or contact our offices in India or the UK.


The Standard Group of Companies offer a range of Rotary Cone Vacuum Dryers to bespoke customer requirements.

The S2 part of the business design, manufacture, assemble, install and commission to user specific requirements (URS).

The key focus is High Precision and Low Temperature Vacuum Drying Mixing Process Technology.

The RCVD facilitates enhanced drying efficiency, low temperature operations and economy of process by total solvent recovery. This supports GMP based working by achieving best practice dust control and gives further advantages of efficient charging and discharging of materials. 

An RCVD is also primarlity used for the drying of materials whose chemistry will not allow a standard drying cycle.

These include: -

  • Resistance to high temperatures.
  • Material which is easily oxidised.
  • Volatile materials which should be retrieved safely.
  • Solvent recovery.
  • Strong irritants.

The S2 RCVD's are completely jacketed for optimum dryer efficiency.

Heat transfer fluid, typically hot water, steam or vapour, is circulated around the conical jacket for even product drying through conduction.

As the dryer rotates, given the shape of the vessel, the entire product batch is thoroughly mixed and high speed dried.

This blending maintains uniform temperatures and eliminates any probability of product re-condensation due to cold spots.

Lasty a high vacuum is used to draw off any remaining moisture while the product is in motion.

The batch is then easily discharged and cleaned given the conical shape of the vessel.


RCVD white lrRotary cone vacuum dryers

Typical technical information: -

  • Design & Construction: AMSE Sec.VIII, Division-I, Latest Edition
  • Main Dimensions: Designed to suit specific applications
  • Flange Drilling: ANSI - B 16.6, #150
  • Capacity: Typically supplied from 300L to 5,000L
  • Operating Pressure: 6 Barg (90 psig)
  • Operating Temperature: up to 200 Deg.C (0-390 Deg F.)


  • Reduces drying time
  • Eliminates need for re-drying of lumps
  • Dry Temperature Sensitive
    • Liquids vaporise at reduced temperature and at reduced pressures, therefore vaporisation of the liquids at very low temperatures is possible.
  • Reduced Energy.
  • Low Cross Contamination.
  • Easily Inspected Interior.
  • Single Enclosed Environment
    • API’s and dangerous chemicals are easily isolated in a vacuum dryer.
  • Avoid Oxidation
    • Using an inert gas oxidation can be avoided.
  • Easily Cleaned
    • The design is ideal for cleaning with a single spray bar.
  • Standardised product with Predictable and Repeatable Results.
    • This feature is essential with any pharmaceutical application

Applications: -

Rotary cone vacuum dryers with unique mixing capabilities are used in the following:- 

  • All pharmaceutical materials
  • Crystalline products
  • Insecticides
  • Pesticides
  • Food products
  • General heat sensitive products.
  • Plastics
  • Agrochemicals
  • Organic chemicals

 For futher infromation click here or contact the Indian or Sheffield offices.